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Norleucine Substitution Enhances Self‐Assembly of a Lanthanide‐Binding Polypeptide Coiled Coil
Sarte, D. B., & Villaraza, A. J. L.
結果: Study utilizes MALDI-TOF MS to confirm the molecular weight and purity of synthetic lanthanide-binding polypeptides featuring norleucine substitutions.
First chemical insights into airborne microbial communities isolated from ambient particulate matter in the Iasi urban area, north-eastern Romania
Iancu, C., Nita, C., Soroaga, L. V., Negru, A. G., Olariu, R. I., & Arsene, C.
結果: MALDI-TOF MS analysis using the α-cyano-4-hydroxycinnamic acid matrix revealed distinct peptide fingerprints for airborne microbial isolates.
Authenticity of cinnamon verum determined by MALDI TOF MS and machine learning
Sarkar, S., & Thompson, J. E.
結果: High-throughput screening of cinnamon varieties using MALDI-TOF MS combined with chemometrics to detect adulteration with C. cassia.
Apelin receptor homodimerisation inhibits hippocampal neuronal autophagy via G protein-dependent signalling in vascular dementia
Cai, X., Hu, S., Liu, W., Yin, Y., Jiang, Y., Wang, Y., Lu, B., Wang, Y., Wang, D., & Chen, J.
結果: Mass spectrometry was employed to characterize protein-protein interactions and signaling pathways involving the Apelin receptor in dementia models.
Diagnostic and Economic Evaluation of MALDI-TOF MS with Machine Learning for Screening of Johne's Disease from Dairy Cow Serum
Sarkar, S., Young, B. A., Daniels, C. S., & Thompson, J. E.
結果: Evaluation of direct-from-serum MALDI-TOF MS profiling as a rapid screening tool for Mycobacterium avium subsp. paratuberculosis.
Proteomic insights into high biohydrogen production by Chlorella sp. KLSc61 under potassium deprivation: upregulation of carbohydrate synthesis proteins
Laokua, N., Dejtisakdi, W., & Maneeruttanarungroj, C.
結果: Label-free quantitative proteomics via LC-MS/MS and MALDI-TOF validation of proteins involved in biohydrogen enhancement in microalgae.
AP-MALDI-MS reveals adulteration of dried oregano leaves
Di Noi, A., Massaro, A., Salvitti, C., Manago, M., Cosentino, F., Piro, R., Suman, M., Pepi, F., Tata, A., & Troiani, A.
結果: Atmospheric Pressure MALDI Mass Spectrometry (AP-MALDI-MS) used for direct fingerprinting of culinary herbs to identify olive leaf adulteration.
Predicting Protein Pathways Associated to Tumor Heterogeneity by Correlating Spatial Lipidomics and Proteomics: The Dry Proteomic Concept
Lagache, L., Zirem, Y., Le Rhun, E., Fournier, I., & Salzet, M.
結果: Integration of MALDI Mass Spectrometry Imaging (MSI) for lipids and subsequent correlation with proteomics to map brain tumor heterogeneity.
Using MALDI‐FTICR Mass Spectrometry to Enhance ZooMS Identifications of Pleistocene Bone Fragments Showing Variable Collagen Preservation
Raymond, P., Ruebens, K., Bray, F., Castel, J. C., Morin, E., Le Brun‐Ricalens, F., Bordes, J. G., Rolando, C., & Hublin, J. J.
結果: Utilization of high-resolution MALDI-FTICR to improve the taxonomic identification of archaeological bone fragments through peptide mass fingerprinting.
Quality-driven divisive K-Means: A new clustering strategy for MALDI imaging data for a more precise and less biased characterization of complex biological tissues
Guerrini, R., Ogrinc, N., Colin, E., Tebbakha, R., Attencourt, C., Boudahi, A., Testelin, S., Dakpé, S., Fournier, I., & Duponchel, L.
結果: A novel unsupervised clustering algorithm designed for processing large MALDI-MSI datasets of biological tissues.
Design, synthesis, molecular modelling investigation and biological studies of novel human carbonic anhydrase inhibitors based on coumalic acid
Pontecorvi, V., Angeli, A., Cutarella, L., Mori, M., Secci, D., Coluccia, M., Carradori, S., Troiani, A., Pepi, F., & Salvitti, C.
結果: Mass spectrometric studies used to confirm identity and purity of novel coumalic acid-derived enzyme inhibitors.
Characterization of the Orphan Cytochrome P450 CYP135B1 from Mycobacterium tuberculosis: Involvement in Metabolism but Not in the Antibacterial Activity of the Antitubercular Drug SQ109
Sadowski, E., Pietrancosta, N., Veyron-Churlet, R., Boucher, J. L., Pionneau, C., Clodic, G., Matheron, L., Poch, O., Mayer, C., & Sachon, E.
結果: Biochemical and mass spectrometric characterization of cytochrome P450 enzymes to investigate drug metabolism in M. tuberculosis.
GCI‐Based Affinity Screening of Synthetic Oligomannosides toward Concanavalin A
Rubes, D., Tengattini, S., Serra, M., Bavaro, T., Temporini, C., Wang, H., Zhang, Y., Rinaldi, F., Terreni, M., & Calleri, E.
結果: MALDI-TOF MS was utilized for the structural verification of synthetic mannosides during affinity screening studies.
Engineering Peptide Modulators for T-Cell Migration by Structural Scaffold Matching
Gattringer, J., Hasinger, S., Weidmann, A., Walczewska-Szewc, K., Jadhav, K. B., Zrzavy, T., Steinmaurer, Anja., Baeten, P., Perisic, M., & Cochrane, W.
結果: High-resolution mass spectrometry was used to validate the synthesis of engineered peptide modulators designed to intercept T-cell trafficking.
Isoelectric Focusing Fractionation Method for Signal Enhancement in Detection of Inactivated Biological Agents Using Matrix‐Assisted Laser Desorption/Ionization Mass Spectrometry
Duša, F., Šalplachta, J., Horká, M., Lunerová, K., Čermáková, V., Dřevínek, M., & Kubíček, O.
結果: Demonstration of IEF fractionation to significantly increase the sensitivity of MALDI-TOF MS in identifying potential bioweapon agents.
Aggregation-Dependent Epitope Sequence and Modification Fingerprints of Anti-Aβ Antibodies
Talucci, I., Leske, T., Klafki, H. W., Mohammed, M. H., Steiert, A., Morgado, B., Bothe, S., Liepold, T., & Walter, J.
結果: MALDI-TOF MS analysis of Amyloid-beta peptides to define binding specificity and post-translational modifications relevant to Alzheimer's disease.
Phytochemical Characterization by Maldi‐tof, Antioxidant and Antimicrobial Activities, and Action Mechanism of Tunisian Thymus Numidicus Extracts
Rahmouni, C., Mendili, M., Aouadhi, C., Jaffali, C., Pizzi, A., & Khadhri, A.
結果: MALDI-TOF MS profiling used to identify key phytochemical constituents in medicinal plant extracts and assess their bioactivity.
Development of a defined medium for the heterotrophic cultivation of Metallosphaera sedula
Sedlmayr, V. L., Luger, M., Pittenauer, E., et al.
結果: The heterotrophic cultivation of extremophilic archaea still heavily relies on complex media. MALDI-TOF MS was used for lipid analysis to verify the composition of the defined medium.
Novel recombinant aminoacylase from Paraburkholderia monticola capable of N-acyl-amino acid synthesis
Haeger, G., Jolmes, T., Oyen, S., et al.
結果: N-Acyl-amino acids can act as mild biobased surfactants. The synthesis products were analyzed by MALDI-TOF MS to confirm the molecular weight of the N-acyl-amino acids.
Water-Soluble Polyglycidol-Grafted Ladder Calix Resorcinarene Oligomers
Penchev, H., Dimitrov, E., Novakov, C., et al.
結果: Ladder oligomers containing calixarene skeletons were synthesized. MALDI-TOF mass spectrometry was used to characterize the molecular weight distribution and structure of the oligomers.
In silico encrypted peptide from green alga Tetraspora sp. CU2551 showed high antimicrobial activities
Tonawut, Y., Rittiyan, N., Kornrawudaphikasama, Y., et al.
結果: Synthetic peptides were synthesized and their purity and molecular mass were checked by MALDI-TOF MS, confirming the potential of algal peptides as antimicrobial agents.
Spidermass and Machine Learning-Based Lipids Immunoscoring Forwards Real Time Ovarian Cancer Diagnosis
Roussel, L., Zirem, Y., Lagache, L., et al.
結果: Development of a robust diagnosis in the operating room using SpiderMass and machine learning based on lipid profiles for ovarian cancer.
Amino‐terminally elongated Aβ peptides are generated by the secreted metalloprotease ADAMTS4
Wirths, O., Lehnen, C., Fricke, M., et al.
結果: Analysis of Aβ peptide profiles using MALDI-TOF MS revealed that ADAMTS4 generates specific N-terminally elongated Aβ variants found in AD brains.
Real-time glioblastoma tumor microenvironment assessment by SpiderMass for improved patient management
Zirem, Y., Ledoux, L., Roussel, L., et al.
結果: Real-time assessment of glioblastoma tumor microenvironment using SpiderMass technology to guide surgical resection and improve patient outcomes.
High-energy CID tandem TOF-MS of various types of precursor ions of selected diether phospholipids
Pittenauer, E., Quehenberger, J., Sedlmayr, V., et al.
結果: Investigation of fragmentation pathways of diether phospholipids using high-energy CID tandem MALDI-TOF MS for structural elucidation.
The ecology, subsistence and diet of ~45,000-year-old Homo sapiens at Ilsenhöhle in Ranis, Germany
Smith, G. M., Ruebens, K., Zavala, E. I., et al.
結果: ZooMS analysis of bone fragments allowed the identification of fauna and human remains, contributing to the understanding of early Homo sapiens ecology.
A co-culture system of macrophages with breast cancer tumoroids to study cell interactions and therapeutic responses
Raffo-Romero, A., Ziane-Chaouche, L., Salomé-Desnoulez, S., et al.
結果: MALDI Mass Spectrometry Imaging (MSI) was used to map the spatial distribution of lipids and metabolites in 3D tumoroid co-culture models.
Practices of the Mont Saint-Michel scriptorium in the use of parchment for manuscripts in the 11th century
Robinet, L., Heu-Thao, S., Arberet, L., et al.
結果: ZooMS analysis was applied to identify the animal species used for parchment production in the Mont Saint-Michel scriptorium.
Activation of the calcium-sensing receptor by a subfraction of amino acids contained in thyroid drainage fluid
Nanoff, C., Yang, Q., Hellinger, R., & Hermann, M.
結果: Analysis of thyroid drainage fluid using mass spectrometry to identify amino acid subfractions activating the calcium-sensing receptor.
Quality evaluation of highly purified human menopausal gonadotropin preparations
Muqaku, L., Dorrer, V., Noe, M., et al.
結果: Mass spectrometry and gel electrophoresis were used to assess the quality and purity of human menopausal gonadotropin preparations.
Strategy for the Identification of Host-Defense Peptides in Frog Skin Secretions
Conlon, J. M., Moffett, R. C., Flatt, P. R., & Leprince, J.
結果: Description of a strategy for purifying and identifying host-defense peptides from frog skin using MALDI-TOF MS for molecular mass determination.
Identification of Secondary Metabolites in Tunisian Tilia platyphyllos Scop. Using MALDI-TOF and GC-MS
Khadhri, A., Mendili, M., Bannour-Scharinger, M., et al.
結果: Phytochemical characterization of Tilia platyphyllos extracts using MALDI-TOF MS to identify secondary metabolites and evaluate biological properties.
Method optimization for benchtop mass spectrometry imaging of lipids in Eisenia hortensis
Selby, K. G., Korte, C. E., Phan, L. H., et al.
結果: Optimization of matrix application methods for high-quality lipid imaging in earthworm tissue using benchtop MALDI-MSI.
Increasing sustainability in palaeoproteomics by optimizing digestion times for large-scale archaeological bone analyses
Le Meillour, L., Sinet-Mathiot, V., Ásmundsdóttir, R. D., et al.
結果: Optimization of trypsin digestion times for ZooMS analysis to increase throughput and sustainability in large-scale archaeological studies.
Boosting the anti-tumor activity of natural killer cells by caripe 8–A Carapichea ipecacuanha isolated cyclotide
List, J., Gattringer, J., Huszarek, S., et al.
結果: Characterization of the cyclotide caripe 8 using MALDI-TOF MS and evaluation of its potential to enhance NK cell anti-tumor activity.
Liquid biopsy of peripheral blood using mass spectrometry detects primary extramedullary disease in multiple myeloma patients
Vlachová, M., Pečinka, L., Gregorová, J., et al.
結果: MALDI-TOF MS profiling of peripheral blood serum was used to detect extramedullary disease markers in multiple myeloma patients.
Characterisation of glucose-induced protein fragments among the order Enterobacterales using MALDI-TOF MS
Kojima, K., Wakabayashi, Y., Nishijima, S., et al.
結果: MALDI-TOF MS analysis was used to identify and characterize glucose-induced protein fragments in Enterobacterales for bacterial identification.
Comparing MS Imaging of Lipids by WALDI and MALDI: Two Technologies for a Common Ground Truth in MS Imaging
Ledoux, L., Zirem, Y., Renaud, F., et al.
結果: Comparison of Water-Assisted Laser Desorption/Ionization (WALDI) and MALDI for lipid imaging, establishing a common ground truth for MS imaging technologies.
Perfusion process for CHO cell producing monoclonal antibody: Comparison of methods to determine optimum cell specific perfusion rate
Maria, S., Bonneau, L., Fould, B., et al.
結果: Optimization of perfusion processes for CHO cells producing monoclonal antibodies, monitored by analytical methods including mass spectrometry.
How the oviduct lipidomic profile changes over time after the start of an obesogenic diet in an outbred mouse model
Moorkens, K., Leroy, J. L., Quanico, J., et al.
結果: Lipidomic profiling of the oviduct in a mouse model using MALDI-TOF MS to understand the impact of an obesogenic diet.
Effect of tryptic digestion on sensitivity and specificity in MALDI-TOF-based molecular diagnostics through machine learning
Sarkar, S., Squire, A., Diab, H., et al.
結果: Investigation of the effect of tryptic digestion on the performance of MALDI-TOF MS-based molecular diagnostics, enhanced by machine learning algorithms.
Chemical mapping of the degradation of geranium lake in paint cross sections by MALDI-MSI
Alvarez-Martin, A., Quanico, J., Scovacricchi, T., et al.
結果: MALDI Mass Spectrometry Imaging (MSI) was used to map the chemical degradation of geranium lake pigment in paint cross-sections.
Insights into the mechanisms governing P01 scorpion toxin effect against U87 glioblastoma cells oncogenesis
Mlayah-Bellalouna, S., Aissaoui-Zid, D., Chantome, A., et al.
結果: Study of the anti-tumor effects of P01 scorpion toxin on glioblastoma cells, characterized using proteomic approaches including MALDI-TOF MS.
Diagnostic screening of bovine mastitis using MALDI-TOF MS direct-spotting of milk and machine learning
Thompson, J., Everhart Nunn, S. L., Sarkar, S., et al.
結果: Development of a rapid diagnostic screening method for bovine mastitis using direct-spotting MALDI-TOF MS of milk samples.
Exploring immune modulatory effects of cyclotide-enriched Viola tricolor preparations
Retzl, B., Zimmermann-Klemd, A. M., Winker, M., et al.
結果: Characterization of cyclotides in Viola tricolor preparations using MALDI-TOF MS to explore their immune modulatory potential.
Self-cross-linked tannin-aminated tannin surface coatings for particleboard
Zhang, B., Pizzi, A., Petrissans, M., et al.
結果: MALDI-TOF MS analysis was used to characterize the structure and oligomer distribution of self-cross-linked tannin-based coatings.
On-resin synthesis of the somatostatin venom analog Consomatin Ro1
de Boda, R. L. B., Acyatan, Z. G., Concepcion, G. P., et al.
結果: Solid-phase synthesis of Consomatin Ro1, a venom analog, with quality control and characterization performed by MALDI-TOF MS.
A melamine-dialdehyde starch wood particleboard surface finish without formaldehyde
Zhang, B., Pizzi, A., Petrissans, M., et al.
結果: Characterization of formaldehyde-free melamine-dialdehyde starch resins for wood finishes using MALDI-TOF MS.
Highly branched tannin-tris (2-aminoethyl) amine-urea wood adhesives
Zhang, B., Chen, X., Pizzi, A., et al.
結果: Structural analysis of highly branched tannin-based wood adhesives using MALDI-TOF mass spectrometry.
Effect of Marinating Temperature of Atlantic Herring on Meat Ripening, Peptide Fractions Proportion, and Antioxidant Activity of Meat and Brine
Szymczak, M., Kamiński, P., Turło, M., et al.
結果: Peptide profiling of marinated Atlantic herring was performed using MALDI-TOF MS to assess the effect of marinating temperature on ripening.